Page 6 - hypertension_newsletter5_draft2

REFLECTIONS
Hypertension
Hypertension Global Newsletter #5 2023

mmHg. Cognitive outcomes included probable dementia, mild cognitive impairment, and the composite of probable dementia or
mild cognitive impairment. Hypertension

In analyzing the baseline characteristics of participants, those with higher TTR were younger, more likely to be men, and less likely
to have a history of ASCVD. The authors found that after adjustment of baseline demographics, medical history, and mean SBP, a
1-standard deviation (31.5%) increase in TTR was independently associated with a 14% lower risk of probable dementia (hazard

CLINICAL PEARLS FROM THE FACULTY ratio, 0.86 [95% CI, 0.76–0.98]; P=0.023). However, there
was no significant association between SBP-TTR and mild
cognitive impairment. A consistent trend was found for a lower
risk of probable dementia associated with higher TTR.

The authors concluded that SBP-TTR was an independent
predictor of probable dementia beyond mean SBP. Maintaining
SBP within 110 to 140 mmHg over time may be beneficial for
dementia prevention. As a novel monitoring metric of blood
pressure control, time in target range could independently
WATCH predict dementia events.
PROF. ARAIZA DISCUSS THE
CLINICAL IMPLICATIONS OF THE
SPRINT MIND STUDY FOR OLDER CLICK HERE
PATIENTS WITH HYPERTENSION. FOR THE LINK TO FULL ARTICLE

TABLE OF CONTENTS